Findings may help predict aggressive colon cancer and identify new treatment targets
This article is alarming because it is identifying a second periodontal pathogen in connection to systemic health. Up to this point one bacteria that is found in aggressive forms of periodontal disease has been indicated in systemic disease, p. Gingivalis. These links to systemic health should be a huge wake up call to anyone with oral disease. If you suspect you or a loved one may have periodontal disease you could be saving a life by having it treated.
COLUMBIA UNIVERSITY IRVING MEDICAL CENTER
Friday, March 15, 2019
Friday, March 1, 2019
Gums and the brain
|Alzheimer's and P. gingivalis linked|
The researchers hope that it will "slow or prevent further neurodegeneration and accumulation of pathology in [Alzheimer's disease] patients."
The heart of the matter
|Links between gum disease and the heart|
|Gum disease could lead to trouble in the bedroom|
However, the link has not been definitively proven. The authors of a review published in 2016 concluded that, although this link seems likely, more large-scale studies are needed.
Gums and lungs
These changes spark inflammation; over the long term, inflammation causes changes in cells that raise the likelihood of cancer developing.
The take-home message
Friday, February 15, 2019
E-cigarette Vaping Impacts Wound Healing
A new study shows that e-cigarette vaping negatively affects skin wound healing, causing damage similar to that of traditional cigarette smoking.
Researchers, led by a team from Boston Medical Center (BMC), found exposure to both e-cigarette vaping and traditional cigarettes in experimental models resulted in increased tissue death, which delays wound healing.
In the study published in JAMA Facial Plastic Surgery, researchers exposed experimental models to one of the following: traditional cigarettes, electronic cigarettes or no cigarettes. They checked serum cotinine levels, a biomarker for exposure to tobacco smoke, in both positive control and experimental groups to ensure that comparable nicotine exposure was achieved in both those groups. Researchers then created skin flaps, which were grafted back on each of the models from which they were created, and then monitored the grafts daily for viability and wound healing. After two weeks, a statistically increased rate of tissue death was found on grafted flaps in groups exposed to either e-cigarettes or traditional cigarettes, according to the study.
“Based on our findings, e-cigarettes are not a safe alternative to traditional cigarettes as it relates to timely wound healing,” says Jeffrey Spiegel, MD, chief of facial plastic surgery at BMC and the study’s corresponding author. “Providers and patients need to understand the risks of both types of smoking so that they can make the best decision to keep the patient as safe as possible before and after surgery.”
Read more of this study in JAMA Facial Plastic Surgery (2018); doi:10.1001/ jamafacial.2018.1179.